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El-Haddad SA, El-Shall MA. New!
Two-Year Clinical Evaluation of Pedicled Buccal Fat Pad Alone and with Emdogain for Root Coverage of Severe Gingival Recession Defects: A Case Series.
Int J Periodontics Restorative Dent. 2017 Nov.Dec;37(6):901-907.
Int J Periodontics Restorative Dent. 2017 Nov.Dec;37(6):901-907.
Hisanaga Y, Suzuki E, Aoki H, Sato M, Saito A, Saito A, Azuma T. New!
Effect of the combined use of enamel matrix derivative and atelocollagen sponge scaffold on osteoblastic differentiation of mouse induced pluripotent stem cells in vitro.
J Periodontal Res. 2017 Oct 17
Shirakata Y, Miron RJ, Shinohara Y, Nakamura T, Sena K, Horai N, Bosshardt DD, Noguchi K, Sculean A. Healing of 2-wall intrabony defects treated with a novel EMD-liquid. A preclinical study in monkeys. J Clin Periodontol. 2017 Oct 1.
Amine K, Amrani YE, Chemlali S, Kissa J. Alternatives to connective tissue graft in the treatment of localized gingival recessions: a systematic review. J Stomatol Oral Maxillofac Surg. 2017 Sep 8. pii: S2468-7855(17)30154-4.
Najeeb S, Khurshid Z, Sohail Zafar M, Zohaib S, Siddiqui F. Efficacy of Enamel Matrix Derivative in Vital Pulp Therapy: A Review of Literature. Iran Endod J. 2017 Summer;12(3):269-275.
Zucchelli G, Mounssif I, Marzadori M, Mazzotti C, Felice P, Stefanini M. Connective Tissue Graft Wall Technique and Enamel Matrix Derivative for the Treatment of Infrabony Defects: Case Reports. Int J Periodontics Restorative Dent. 2017 Sep/Oct;37(5):673-68
Devji T. Inconclusive evidence about whether the addition of enamel matrix derivatives to bone substitutes yields better clinical outcomes for treatment of intrabony defects. J Am Dent Assoc. 2017 Aug 5
Cairo F. Periodontal plastic surgery of gingival recessions at single and multiple teeth. Periodontol 2000. 2017 Oct;75(1):296-316.
Sangiorgio JP, Lucas da Silva Neves F, Santos MRD, França-Grohmann IL, Corrêa Viana Casarin R, Casati MZ, Pedrine Santamaria M, Sallum EA. Xenogenous Collagen Matrix and/or Enamel Matrix Derivative for Treatment of Localized Gingival Recessions - a Randomized Clinical Trial. Part I: Clinical Outcomes. J Periodontol. 2017 Jul 28:1-15.
Santos MRD, Sangiorgio JPM, Lucas da Silva Neves F, França-Grohmann IL, Humberto Nociti F Junior, Gonzales Silverio Ruiz K, Pedrine Santamaria M, Sallum EA. Xenogenous Collagen Matrix and/or Enamel Matrix Derivative for Treatment of Localized Gingival Recessions - a Randomized Clinical Trial. Part II: Patient-Reported Outcomes.

J Periodontol. 2017 Jul 28:1-14.
Aslan S, Buduneli N, Cortellini P. Entire papilla preservation technique in the regenerative treatment of deep intrabony defects: 1-year results. J Clin Periodontol. 2017 Jul 20.
Seshima F, Aoki H, Takeuchi T, Suzuki E, Irokawa D, Makino-Oi A, Sugito H, Tomita S, Saito A. Periodontal regenerative therapy with enamel matrix derivative in the treatment of intrabony defects: a prospective 2-year study. BMC Res Notes. 2017 Jul 6;10(1):256
Seshima F, Aoki H, Takeuchi T, Suzuki E, Irokawa D, Makino-Oi A, Sugito H, Tomita S, Saito A. Periodontal regenerative therapy with enamel matrix derivative in the treatment of intrabony defects: a prospective 2-year study. BMC Res Notes. 2017 Jul 6;10(1):256
Yoo HI, Lee GH, Lee SY, Kang JH, Moon JS, Kim MS, Kim SH. Expression of amelogenin and effects of cyclosporin A in developing hair follicles in rats. J Anat. 2016 Jan;228(1):153-61.
Liu Y, Hu B, Zhou J, Li W, Liu Q, Song J. The Effect of Enamel Matrix Derivative Alone Versus in Combination with Alloplastic Materials to Treat Intrabony Defects: A Meta-analysis. Int J Periodontics Restorative Dent. 2017 Jul/Aug;37(4):e224-e233.
Sakaguchi K, Katagiri W, Osugi M, Kawai T, Sugimura-Wakayama Y, Hibi H. Periodontal tissue regeneration using the cytokine cocktail mimicking secretomes in the conditioned media from human mesenchymal stem cells. Biochem Biophys Res Commun. 2017 Feb 26;484(1):100-106.
Li G, Hu J, Chen H, Chen L, Zhang N, Zhao L, Wen N, Yang Y. Enamel matrix derivative enhances the proliferation and osteogenic differentiation of human periodontal ligament stem cells on the titanium implant surface. Organogenesis. 2017 Jun 9:0.
Shi B, Andrukhov O, Özdemir B, Shokoohi Tabrizi HA, Dard M, Rausch-Fan X. Effect of enamel matrix derivative on the angiogenic behaviors of human umbilical vein endothelial cells on different titanium surfaces. Dent Mater J. 2017 May 30.
Apicella A, Heunemann P, Dejace L, Marascio M, Plummer CJG, Fischer P. Scaffold requirements for periodontal regeneration with enamel matrix derivative proteins. Colloids Surf B Biointerfaces. 2017 May 9;156:221-226.
Troiano G, Laino L, Zhurakivska K, Cicciù M, Lo Muzio L, Lo Russo L. Addition of enamel matrix derivatives to bone substitutes for the treatment of intrabony defects: a systematic review, meta-analysis and trial sequential analysis. J Clin Periodontol. 2017 May 6.
Nery JC, Pereira LAVD, Guimarães GF, Scardueli CR, França FMG, Spin-Neto R, Stavropoulos A. β-TCP/HA with or without enamel matrix proteins for maxillary sinus floor augmentation: a histomorphometric analysis of human biopsies. Int J Implant Dent. 2017 Dec;3(1):18.. Epub 2017 May 4.
Wyganowska-Swiatkowska M, Urbaniak P, Lipinski D, Szalata M, Kotwicka M. Human gingival fibroblast response to enamel matrix derivative, porcine recombinant 21.3-kDa amelogenin and 5.3-kDa tyrosine-rich amelogenin peptide. Hum Cell. 2017 May 3.
Madeley E, Duane B. Coronally advanced flap combined with connective tissue graft; treatment of choice for root coverage following recession?
Madeley E, Duane B.
Evid Based Dent. 2017 Mar;18(1):6-7.
Alexiou A, Vouros I, Menexes G, Konstantinidis A. Comparison of enamel matrix derivative (Emdogain) and subepithelial connective tissue graft for root coverage in patients with multiple gingival recession defects: A randomized controlled clinical study.
Alexiou A, Vouros I, Menexes G, Konstantinidis A.
Quintessence Int. 2017;48(5):381-389.
Quintessence Int. 2017;48(5):381-389.
Queiroz LA, Casarin RC, Dabdoub SM, Tatakis DN, Sallum EA, Kumar PS. Furcation Therapy With Enamel Matrix Derivative: Effects on the Subgingival Microbiome. J Periodontol. 2017 Mar 17:1-11.
Wu YC, Lin LK, Song CJ, Su YX, Tu YK. Comparisons of Periodontal Regenerative Therapies: A Meta-Analysis on the Long-term Efficacy. J Clin Periodontol. 2017 Mar 9.
Liu Y, Duan D, Xin Y, Bai L, Li T, Li C, Xu Y. A review of the literature: antibiotic usage and its relevance to the infection in periodontal flaps. Acta Odontol Scand. 2017 Mar 10:1-6.
Stakkestad Ø, Lyngstadaas SP, Vondrasek J, Gordeladze JO, Reseland JE. Ameloblastin Peptides Modulates the Osteogenic Capacity of Human Mesenchymal Stem Cells. Front Physiol. 2017 Feb 7;8:58.
Buduneli E, Buduneli N. Re: Evaluation of the adjunctive effect of platelet-rich fibrin to enamel matrix derivative in the treatment of intrabony defects. Six-month results of a randomized, split-mouth, controlled clinical study.
Buduneli E, Buduneli N.
J Clin Periodontol. 2017 Feb 10.
J Clin Periodontol. 2017 Feb 10.
Aslan S, Buduneli N, Cortellini P. Entire Papilla Preservation Technique: A Novel Surgical Approach for Regenerative Treatment of Deep and Wide Intrabony Defects. Int J Periodontics Restorative Dent. 2017 Mar/Apr;37(2):227-233
Jiang T, Liu F, Wang WG, Jiang X, Wen X, Hu KJ, Xue Y.
PLoS One. 2017 Jan 17;12(1):e0169857.
Distribution of Cathepsin K in Late Stage of Tooth Germ Development and Its Function in Degrading Enamel Matrix Proteins in Mouse. PLoS One. 2017 Jan 17;12(1):e0169857.
Kaner D, Soudan M, Zhao H, Gaßmann G, Schönhauser A, Friedmann A. Early Healing Events after Periodontal Surgery: Observations on Soft Tissue Healing, Microcirculation, and Wound Fluid Cytokine Levels. Int J Mol Sci. 2017 Jan 27;18(2).
Miron RJ, Fujioka-Kobayashi M, Buser D, Zhang Y, Bosshardt DD, Sculean A. Combination of Collagen Barrier Membrane with Enamel Matrix Derivative-Liquid Improves Osteoblast Adhesion and Differentiation.
Int J Oral Maxillofac Implants. 2017 Jan/Feb;32(1):196-203.
執筆者
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Kashefimehr A, Pourabbas R, Faramarzi M, Zarandi A, Moradi A, Tenenbaum HC, Azarpazhooh A. Effects of enamel matrix derivative on non-surgical management of peri-implant mucositis: a double-blind randomized clinical trial. Clin Oral Investig. 2016 Dec 30.
Bollu IP, Velagula LD, Bolla N, Kumar KK, Hari A, Thumu J. Histological evaluation of mineral trioxide aggregate and enamel matrix derivative combination in direct pulp capping: An in vivo study. J Conserv Dent. 2016 Nov-Dec;19(6):536-540.
Shirakata Y, Miron RJ, Nakamura T, Sena K, Shinohara Y, Horai N, Bosshardt DD, Noguchi K, Sculean A. Effects of EMD-liquid (Osteogain) on periodontal healing in class III furcation defects in monkeys. J Clin Periodontol. 2016 Dec 15.
Losada M, González R, Pujol À, Santos A, Nart J. Treatment of Non-Contained Infrabony Defects With Enamel Matrix Derivative Alone or in Combination With a Biphasic Calcium Phosphate Bone Graft: a 12-Month Randomized Controlled Clinical Trial. J Periodontol. 2016 Dec 13:1-14.
Miron RJ, Fujioka-Kobayashi M, Zhang Y, Sculean A, Pippenger B, Shirakata Y, Kandalam U, Hernandez M. Osteogain® loaded onto an absorbable collagen sponge induces attachment and osteoblast differentiation of ST2 cells in vitro. Clin Oral Investig. 2016 Dec 1.
Seshima F, Nishina M, Namba T, Saito A. Periodontal Regenerative Therapy in Patient with Chronic Periodontitis and Type 2 Diabetes Mellitus: A Case Report.

Bull Tokyo Dent Coll. 2016;57(2):97-104.

 

Parra C, Jeong YN, Hawley CE. Guided Tissue Regeneration Involving Piercing-Induced Lingual Recession: A Case Report. Int J Periodontics Restorative Dent. 2016 Nov/Dec;36(6):869-875.
Jonke E, Gemperli AC, Zhang T, Özdemir B, Dard M, Rausch-Fan X, Andrukhov O. Effect of tyrosine-rich amelogenin peptide on behavior and differentiation of endothelial cells. Clin Oral Investig. 2016 Nov;20(8):2275-2284.
Aimetti M, Ferrarotti F, Mariani G, Fratini A, Giraudi M, Romano F. Enamel Matrix Derivative Proteins in Combination with a Flapless Approach for Periodontal Regeneration of Intrabony Defects: A 2-Year Prospective Case Series. Int J Periodontics Restorative Dent. 2016 Nov/Dec;36(6):797-805.
Isehed C, Holmlund A, Renvert S, Svenson B, Johansson I, Lundberg P. Effectiveness of enamel matrix derivative on the clinical and microbiological outcomes following surgical regenerative treatment of peri-implantitis. A randomized controlled trial.
J Clin Periodontol. 2016 Oct;43(10):863-73.
Kobayashi-Kinoshita S, Yamakoshi Y, Onuma K, Yamamoto R, Asada Y. TGF-β1 autocrine signalling and enamel matrix components.
Sci Rep. 2016 Sep 16;6:33644.
Liu F, Zhou ZF, An Y, Yu Y, Wu RX, Yin Y, Xue Y, Chen FM. Effects of cathepsin K on Emdogain-induced hard tissue formation by human periodontal ligament stem cells.
J Tissue Eng Regen Med. 2016 Jul 12.
Isehed C, Holmlund A, Renvert S, Svenson B, Johansson I, Lundberg P.
Effectiveness of enamel matrix derivative on the clinical and microbiological outcomes following surgical regenerative treatment of peri-implantitis. A randomized controlled trial.

 

J Clin Periodontol. 2016 May 18.
Ghezzi C, Ferrantino L, Bernardini L, Lencioni M, Masiero S. Minimally Invasive Surgical Technique in Periodontal Regeneration: A Randomized Controlled Clinical Trial Pilot Study.
Int J Periodontics Restorative Dent. 2016 Jul-Aug;36(4):475-82.
Costa PP, Alves LB, Souza SL, Grisi MF, Palioto DB, Taba M Jr, Novaes AB Jr. Root Coverage in Smokers with Acellular Dermal Matrix Graft and Enamel Matrix Derivative: A 12-Month Randomized Clinical Trial.
Int J Periodontics Restorative Dent. 2016 Jul-Aug;36(4):525-31.
Groeger S, Windhorst A, Meyle J. Influence of Enamel Matrix Derivative (EMD) on Human Epithelial Cells in Vitro.
J Periodontol. 2016 Jun 17:1-17.
Aydemir Turkal H, Demirer S, Dolgun A, Keceli HG. Evaluation of the adjunctive effect of platelet rich fibrin to enamel matrix derivative in the treatment of intrabony defects. Six months results of a randomized, split-mouth, controlled clinical study.
J Clin Periodontol. 2016 Jul 10.
Taniguchi Y, Aoki A, Sakai K, Mizutani K, Meinzer W, Izumi Y. A Novel Surgical Procedure for Er:YAG Laser-Assisted Periodontal Regenerative Therapy: Case Series. Int J Periodontics Restorative Dent. 2016 Jul-Aug;36(4):507-15.
Agrali ÖB, Kuru BE, Yarat A, Kuru L. Evaluation of gingival crevicular fluid transforming growth factor-β1 level after treatmentof intrabony periodontal defects with enamel matrix derivatives and autogenous bone graft: A randomized controlled clinical trial. Niger J Clin Pract. 2016 Jul-Aug;19(4):535-43.
白方良典,野口和行
鹿児島大学大学院医歯学総合研究科歯周病学分野
歯周組織再生療法におけるエナメルマトリックスデリバティブと骨移植材の併用効果を再考する

 

 

日歯周誌58(1):1-15,2016
佐々木大輔,八重柏隆
岩手医科大学歯学部歯科保存学講座歯周療法学分野
EMD の現在―生誕20 年にあたり― 日歯周誌57(4):135-142,2015
Yoshimi Y, Kunimatsu R, Hirose N, Awada T, Miyauchi M, Takata T, Wu L, Zhu L, Denbesten P, Tanne K, Tanimoto K. Effects of C-Terminal Amelogenin Peptide on the Proliferation of Human Cementoblast Lineage Cells.  
Kunimatsu R, Yoshimi Y, Hirose N, Awada T, Miyauchi M, Takata T, Li W, Zhu L, Denbesten PK, Tanimoto K. The C-terminus of amelogenin enhances osteogenic differentiation of human cementoblast lineage cells. J Periodontal Res. 2016 May 5.
Sugaya T, Tomita M, Motoki Y, Miyaji H, Kawamami M. Influence of enamel matrix derivative on healing of root surfaces after bonding treatment and intentional replantation of vertically fractured roots. Dent Traumatol. 2016 Mar 21.
Abu-Ta'a M. Adjunctive Systemic Antimicrobial Therapy vs Asepsis in Conjunction with Guided Tissue Regeneration: A Randomized, Controlled Clinical Trial. J Contemp Dent Pract. 2016 Jan 1;17(1):3-6.
Yoshimi Y, Kunimatsu R, Hirose N, Awada T, Miyauchi M, Takata T, Wu L, Zhu L, Denbesten P, Tanne K, Tanimoto K. Effects of C-Terminal Amelogenin Peptide on the Proliferation of Human Cementoblast Lineage Cells. J Periodontol. 2016 Apr 4:1-20.
Kunimatsu R, Yoshimi Y, Hirose N, Awada T, Miyauchi M, Takata T, Li W, Zhu L, Denbesten PK, Tanimoto K. The C-terminus of amelogenin enhances osteogenic differentiation of human cementoblast lineage cells.
J Periodontal Res. 2016 May 5.
Sugaya T, Tomita M, Motoki Y, Miyaji H, Kawamami M. Influence of enamel matrix derivative on healing of root surfaces after bonding treatment and intentional replantation of vertically fractured roots. Dent Traumatol. 2016 Mar 21.
Abu-Ta'a M. Adjunctive Systemic Antimicrobial Therapy vs Asepsis in Conjunction with Guided Tissue Regeneration: A Randomized, Controlled Clinical Trial.

 

J Contemp Dent Pract. 2016 Jan 1;17(1):3-6.
Aimetti M, Ferrarotti F, Mariani GM, Romano F. A novel flapless approach versus minimally invasive surgery in periodontal regeneration with enamel matrix derivative proteins: a 24-month randomized controlled clinical trial.
Clin Oral Investig. 2016 Apr 5.
Yoshimi Y, Kunimatsu R, Hirose N, Awada T, Miyauchi M, Takata T, Wu L, Zhu L, Denbesten P, Tanne K, Tanimoto K. Effects of C-Terminal Amelogenin Peptide on the Proliferation of Human Cementoblast Lineage Cells. J Periodontol. 2016 Apr 4:1-20.
Schwendicke F, Brouwer F, Schwendicke A, Paris S. Different materials for direct pulp capping: systematic review and meta-analysis and trial sequential analysis. Clin Oral Investig. 2016 Apr 2.
Liu J, Saito K, Maruya Y, Nakamura T, Yamada A, Fukumoto E, Ishikawa M, Iwamoto T, Miyazaki K, Yoshizaki K, Ge L, Fukumoto S. Mutant GDF5 enhances ameloblast differentiation via accelerated BMP2-induced Smad1/5/8 phosphorylation.

Sci Rep. 2016 Mar 31
Schmidlin P, Zobrist K, Attin T, Wegehaupt F. In vitro re-hardening of artificial enamel caries lesions using enamel matrix proteins or self-assembling peptides.

J Appl Oral Sci. 2016 Feb;24(1):31-6.
Miron RJ, Sculean A, Cochran DL, Froum S, Zucchelli G, Nemcovsky C, Donos N, Lyngstadaas SP, Deschner J, Dard M, Stavropoulos A, Zhang Y, Trombelli L, Kasaj A, Shirakata Y, Cortellini P, Tonetti M, Rasperini G, Jepsen S, Bosshardt DD. 20 years of Enamel Matrix Derivative: The past, the present and the future.

J Clin Periodontol. 2016 Mar 14. doi: 10.1111/jcpe.12546.
Villa O, Wohlfahrt JC, Koldsland OC, Brookes SJ, Lyngstadaas SP, Aass AM, Reseland JE. EMD in periodontal regenerative surgery modulates cytokine profiles: A randomised controlled clinical trial. Sci Rep. 2016 Mar 15
Morand DN, Davideau JL, Clauss F, Jessel N, Tenenbaum H, Huck O. Cytokines during periodontal wound healing: potential application for new therapeutic approach. Oral Dis. 2016 Mar 4.
Miron RJ, Fujioka-Kobayashi M, Zhang Y, Caballé-Serrano J, Shirakata Y, Bosshardt DD, Buser D, Sculean A Osteogain improves osteoblast adhesion, proliferation and differentiation on a bovine-derived natural bone mineral. Clin Oral Implants Res.2016 Feb 26
Jonke E, Gemperli AC, Zhang T, Ozdemir B, Dard M, Rausch-Fan X, Andrukhov O. Effect of tyrosine-rich amelogenin peptide on behavior and differentiation of endothelial cells. Clin Oral Investig. 2016 Feb 12.
McGuire MK, Scheyer ET, Schupbach P. A Prospective, Cased-Controlled Study Evaluating the use of Enamel Matrix Derivative on Human Buccal Recession Defects: A Human Histologic Examination. J Periodontol.2016 Feb 1:
Wang Z, Feng Z, Wu G, Bai S, Dong Y, Zhao Y. In vitro studies on human periodontal ligament stem cell sheets enhanced by enamel matrix derivative. Colloids Surf B Biointerfaces.2016 Jan 22;141:102-111.
Maymon-Gil T, Weinberg E, Nemcovsky C, Weinreb M. Enamel Matrix Derivative Promotes Healing of a Surgical Wound in the Rat Oral Mucosa. J Periodontol. 2016 Jan 16:
Stahli A, Miron RJ, Bosshardt DD, Sculean A, Gruber R. Collagen Membranes Adsorb the Transforming Growth Factor-β Receptor I Kinase-dependent Activity of Enamel Matrix Derivative. J Periodontol. 2016 Jan 16:
Lu X, Fukumoto S, Yamada Y, Evans CA, Diekwisch TG, Luan X. Ameloblastin, an Extracellular Matrix Protein, Affects Long Bone Growth and Mineralization. J Bone Miner Res. 2016 Jan 13.
Miron RJ, Shuang Y, Sculean A, Buser D, Chandad F, Zhang Y. Gene array of PDL cells exposed to Osteogain in combination with a bone grafting material. Clin Oral Investig. 2016 Jan 8.
Stahli A, Miron RJ, Bosshardt DD, Sculean A, Gruber R. Collagen Membranes Adsorb the Transforming Growth Factor-β Receptor I Kinase-dependent Activity of Enamel Matrix Derivative. J Periodontol. 2016 Jan 16:
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タイトル
掲載誌, 号, ページ
Simion M, Ferrantino L, Idotta E, Maglione M. The Association of Guided Bone Regeneration and Enamel Matrix Derivative for Suprabony Reconstruction in the Esthetic Area: A Case Report. Int J Periodontics Restorative Dent. 2015 Nov-Dec;35(6):767-72.